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Androgenic anabolic steroid use correlates with both illicit drug use and prescription drug abuse, which are particularly prevalent in youth.1,4–5 While drug abuse is associated with a wide range of medical adverse effects including liver and breast cancer,8,9,10 and is associated with serious health consequences,11,12 and cardiovascular morbidity and mortality,13 only two major studies have focused on the effects of anabolic use on mental health, and neither has found a significant association between adolescent anabolic steroid use and psychological problems.14,15 A number of recent studies are examining the association between anabolic steroid use and self-harm, suicidal ideation, suicidal attempts, and life satisfaction, in particular in adolescents.1,16–20 A recent study among high school students indicated that those with a history of use of anabolic steroids had significantly greater suicidal ideation than those without use, and greater mental health problems than those with no anabolic steroid history.21 In addition, a national study based on the Youth Risk Behavior Survey found that current adolescents who reported using anabolic steroids had better mental control scores compared to students who had never used them.22 Studies examining potential biological correlates of adolescent anabolic steroid use have primarily relied on clinical studies, with no significant longitudinal design.23–25 This article examines whether adolescents who use anabolic steroids have poorer mental health, depressive symptoms, suicidal ideation, and self-harm compared to nonusers. We also examine self-harm in terms of severity, the number of days in a month during the last 12 months, and duration of anabolic steroid use, to better examine whether anabolic steroid use contributes to mental health problems among adolescents. Methods Design The National Survey of Student Engagement (National Longitudinal Study of Youth 2007–2011) was conducted by the National Institute of Child Health and Human Development; the data provided for this article came from this survey (Table 1). Information on drug use at baseline and at the four-year visit is described in the supplementary materials. A total of 2,972 adolescents aged 13 to 17 (including 852 girls) participated. Informed written consent was obtained from all participants and the institutional review boards of both the National Institute for Substance Abuse Research and the National Institute on Alcohol Abuse and Alcoholism approved this study. Table 1. Sample Characteristics Source of Study Participant Gender Age 17+ Years 852 White/Caucasian 842 Female 842 African American/Black 842 Latino 842 Other 733 Current Students of a High School Ethnicity White 87% White/Other 2 Similar articles: